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<p>그림 5. 면역/기질세포 침윤, 세포 간 소통 및 특징적 활성화에 대한 공간적 전사체 분석 전체 캡션 표시 그림 뷰어 다음으로 공간 전사체 데이터를 사용하여 염증성 veHCC에서 면역 회피 특성을 분석했습니다. SOAPy 48 을 통해 확인된 공간적 세포 간 상호작용 은 CD8 + T 세포가 CD4 + T 세포, CAFs, 대식세포를 포함한 다양한 세포 유형과 광범위한 상호작용을 한다는 것을 보여주었습니다( 그림 5D ~5F). 특히, CD4 + T 세포는 3개의 염증성 veHCC 모두에서 CD8 + T 세포 와 가장 많은 리간드-수용체 상호작용을 나타냈습니다 ( 그림 5D ~5F). 공간적으로, CD4 + 및 CD8 + T 세포는 서로 매우 가깝게 위치하여 뚜렷한 세포 클러스터를 형성했습니다( 그림 5G , 5H 및 S7E ). Treg 세포 및 소진된 T 세포의 특징 점수 분석 결과, CD4 + 및 CD8 + T 세포가 밀집된 영역에서 이러한 세포들의 활성화가 두드러지게 나타났습니다 ( 그림 5I ~5L, S7F 및 S7G). <a class="seoquake-nofollow" href="https://www.actionz.org/주소콘" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span style="color:rgb(255,255,255);font-family:LexiSaebomR;line-height:2;letter-spacing:1px;text-decoration:none;">주소콘</span></a> <a class="seoquake-nofollow" href="https://www.actionz.org/링크모음" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span style="color:rgb(255,255,255);font-family:LexiSaebomR;line-height:2;letter-spacing:1px;text-decoration:none;">링크모음</span></a> <a class="seoquake-nofollow" href="https://www.xn--vg1b90m0qhtja.com/" rel="nofollow noreferrer noopener" style="font-size:0;line-height:0;text-decoration:none;" target="_blank"> <span 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